Etofenprox 醚菊酯

醚菊酯

简介
英文通用名称 ethofenprox
其他名称 MTI-500，多来宝

毒性
醚菊酯属低毒杀虫剂。急性经口LD50：雄大鼠>21440mg/kg，雌大鼠>42880mg/kg，雄小鼠>53600mg/kg，雌小鼠>107200mg/kg。急性经皮LD50：雄大鼠>1072mg/kg，雌小鼠>2140mg/kg。对皮肤和眼睛无刺激作用。对鱼和蜜蜂高毒。

剂型与含量
10%醚菊酯悬浮剂

产品特点：
1、击倒速度快，杀虫活性高、具有触杀和胃毒的特性。药后30分钟能达到50%以上。
2、持效期较长的特性，正常情况下持效期20天以上
3、具有杀虫谱广,(见适用范围）
4、对作物安全、对天敌安全。
（采摘自中国农药电子手册）

适用范围：
适用于防治水稻、蔬菜、棉花上，对同翅目飞虱科特效，同时对鳞翅目、半翅目、直翅目、鞘翅目、双翅目和等翅目等多种害虫也有很好的效果。 尤其对水稻稻飞虱的防治效果显著。同时也是国家禁止高毒类农药在水稻上应用后的指定产品。
特别提示：醚菊酯不属于菊酯类农药
在的结构中无菊酸但因空间结构和拟除虫菊酯有相似之处，所以仍称为类似拟除虫菊酯类的杀虫剂，但是事实上醚菊酯不属于拟虫菊酯类农药，而是属于醚类，但是兼具了拟虫菊酯类农药的优点，具有杀虫杀虫活性高、击倒速度快的特点。

使用方法
1、防治水稻灰飞虱、白背飞虱、褐飞虱每亩用10%悬浮剂30-40ml，防治水稻稻象甲，每亩用10%悬浮剂40-50ml，对水喷雾。
醚菊酯是唯一允许在水稻上登记的拟虫菊酯类农药。 速效性和持效性优于吡蚜酮和烯啶虫胺。自2009年起，醚菊酯已经被全国农技推广中心列入重点推广产品，2009年起安徽、江苏、湖北、湖南、广西等地植保站已经将药剂列入植保站重点推广品种。
2、防治甘蓝青虫、甜菜夜蛾、斜纹夜蛾，每亩用10%悬浮剂40ml对水喷雾。
3、防治松毛虫，10%悬浮剂以30-50mg药液喷雾。
4、防治棉花害虫，如棉铃虫、烟草夜蛾、棉红铃虫等，每亩用10%悬浮剂30-40ml，对水喷雾。
5、防治玉米螟、大螟等，每亩用10%悬浮剂30-40ml，对水喷雾。

注意事项
1、使用时避免污染鱼塘、蜂场。
2、使用时若不慎中毒，应立即就医。
生产厂家有潍坊万胜生物农药有限公司。,产品为稻飞龙。

etofenprox
Insecticide
IRAC 3; non-ester pyrethroid

NOMENCLATURE
Common name etofenprox ((m) draft F-ISO, INN; BSI, draft E-ISO both since 1988); ethofenprox* (before 1988)
IUPAC name 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzyl ether
Chemical Abstracts name 1-[[2-(4-ethoxyphenyl)-2-methylpropoxy]methyl]-3-phenoxybenzene
CAS RN [80844-07-1] Development codes MTI-500 (Mitsui) Official codes OMS 3002

PHYSICAL CHEMISTRY
Mol. wt. 376.5 M.f. C25H28O3 Form White crystals. M.p. 36.4-38.0 ºC B.p. 200 ºC/0.18 mmHg V.p. 32 mPa (100 ºC) KOW logP = 7.05 (25 ºC) S.g./density 1.157 (23 ºC, solid); 1.067 (40.1 ºC, liquid) Solubility In water <1 mg/l (25 ºC). In chloroform 9, acetone 7.8, ethyl acetate 6, xylene 4.8, methanol 0.066 (all in kg/l, 25 ºC). Stability Stable in acidic and alkaline media at 80 ºC for >90 days, and to light.

COMMERCIALISATION
History Insecticide introduced in Japan (1987) by Mitsui Toatsu Chemicals, Inc. (now Mitsui Chemicals Inc.). Patents GB 2118167; US 4570005 Manufacturers Mitsui; RPG

APPLICATIONS
Biochemistry Acts on the nervous system of insects, disturbs the function of neurons by interaction with the sodium channel. Mode of action Insecticide with contact and stomach action. Uses Control of rice water weevils, skippers, leaf beetles, leafhoppers, planthoppers, and bugs on paddy rice; and aphids, moths, butterflies, whitefly, leaf miners, leaf rollers, leafhoppers, thrips, borers, etc. on pome fruit, stone fruit, citrus fruit, tea, soya beans, sugar beet, brassicas, cucumbers, aubergines, and other crops. Also used to control public health pests, and on livestock. Formulation types CS; DP; EW; EC; GR; SL; UL; WP. Selected products: 'Trebon' (Mitsui); 'Boxer' (Vapco)

OTHER PRODUCTS
'Nukil' (Mitsui, Dhanuka); 'Vectron' (Mitsui); 'Primo' (RPG) mixtures: 'Achieve Moncut Trebon' (+ fenoxanil+ flutolanil) (Nihon Nohyaku); 'Kasu-rab-validatrebon' (+ kasugamycin hydrochloride hydrate+ phthalide+ validamycin) (Hokko); 'Mon-Rab Trebon F' (+ flutolanil+ phthalide) (Nihon Nohyaku); 'Vicidi-M' (+ phenthoate) (Vipesco)

ANALYSIS
Product analysis by glc with FID (CIPAC Handbook, 1995, G, 56-61). Residues determined by glc with ECD.

MAMMALIAN TOXICOLOGY
Reviews FAO/WHO 68, 70 (see part 2 of the Bibliography). Oral Acute oral LD50 for male and female rats >42 880, male mice >107 200, dogs >5000 mg/kg. Skin and eye Acute percutaneous LD50 for rats and male and female mice >2140 mg/kg; non-irritating to skin and eyes (rabbits). Inhalation LC50 (4 h) for rats 5900 mg/m3. NOEL (1 y) for dogs 32 mg/kg diet; (2 y) for male rats 3.7, female rats 4.8, male mice 3.1, female mice 3.6 mg/kg diet. In life-span feeding studies on rats and mice, at doses up to 4900 ppm, and on dogs, at doses up to 10 000 ppm, no adverse effects were observed. Mutagenicity, teratogenicity, and three-generation reproduction studies showed no noticeable abnormalities. ADI (JMPR) 0.03 mg/kg b.w. [1993]. Toxicity class WHO (a.i.) U; EPA (formulation) IV

ECOTOXICOLOGY
Birds Acute oral LD50 for mallard ducks >2000 mg/kg. Fish TLm (48 h) for carp 5.0 ppm. Daphnia LC50 (3 h) >40 mg/l. Worms LC50 for earthworms (7 d) 43.1 ppm, (14 d) 24.6 ppm.

ENVIRONMENTAL FATE
Animals In rats, parent compound, 2-(4-hydroxyphenyl)-2-methylpropyl 3-(phenoxybenzyl) ether, and 2-(4-ethoxyphenyl)-2-methylpropyl 3-(4-hydroxybenzyl) ether are found. Plants In rice, the main metabolite is 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate. Soil/Environment DT50 in soil c. 6 d.