Diclocymet 双氯氰菌胺

中文通用名称： 双氯氰菌胺
英文通用名称： diclocymet
商品名称： Delaus
化学名称：
(RS)-2-氰基-N-(R)-1-(2,4-二氯苯基)乙基]-3,3-二甲基丁酰胺
(RS)-2-cyano-N-(R)-1-(2,4-dichlorophenyl)ethyl]-3,3-dimethylbutanamide
CA主题索引名及CAS登录号
(RS)-2-cyano-N-(R)-1-(2,4-dichlorophenyl)ethyl]-3,3-dimethylbutanamide
[139920-32-4]

理化性质：淡黄色结晶，密度1.24 (23 °C); 熔点:154.4-156.6 °C; 蒸汽压:2.6×10-1 mPa (25 °C); 水中溶解度 6.38 mg/l (25 °C).

毒性：大鼠经口LD50（mg/kg ）>5,000，经皮LD50（mg/kg ）>2,000，吸入LC50（mg/L）>1.18，对眼有轻度刺激，对皮肤无刺激性。

化学结构类型：酰胺类

应用：内吸性杀菌剂，主要用于防治稻瘟病。

作用特点及用途：黑色素生物合成抑制剂。内吸性杀菌剂，以每公顷90~120 ｇ 用量防治稻瘟病。

生产方法：

剂型：3%颗粒剂 ，7.5%悬浮液

diclocymet
Fungicide
FRAC 16.2, I2; MBI: dehydratase

NOMENCLATURE
Common name diclocymet (BSI, pa ISO)
IUPAC name (RS)-2-cyano-N-[(R)-1-(2,4-dichlorophenyl)ethyl]-3,3-dimethylbutyramide
Chemical Abstracts name 2-cyano-N-[(1R)-(2,4-dichlorophenyl)ethyl]-3,3-dimethylbutanamide
CAS RN [139920-32-4] (for (RS)- (RS)- mixture) Development codes S-2900 (Sumitomo)

PHYSICAL CHEMISTRY
Mol. wt. 313.2 M.f. C15H18Cl2N2O Form Pale yellow, crystalline solid. M.p. 154.4-156.6 °C V.p. 2.6 ´ 10-1 mPa (25 °C) S.g./density 1.24 (23 °C) Solubility In water 6.38 mg/ml (25 °C).

COMMERCIALISATION
History Reported by A. Manabe et al., Proc. 9th IUPAC Int. Congr. Pestic. Chem., London, 1998, 1, 1B-016. Under development by Sumitomo Chemical Co. Ltd. Patents JPH02-76846 Manufacturers Sumitomo

APPLICATIONS
Biochemistry Inhibits melanin biosynthesis. Uses Under development for control of rice blast. Selected products: 'Delaus' (Sumitomo)

OTHER PRODUCTS
Mixtures: 'Delausdantotsu' (+ clothianidin) (Sumitomo Chemical Takeda); 'Delaus-Prince' (+ fipronil) (Nissan)

MAMMALIAN TOXICOLOGY
Oral Acute oral LD50 for male and female rats >5000 mg/kg. Skin and eye Acute dermal LD50 for male and female rats >2000 mg/kg.

ECOTOXICOLOGY
Fish LC50 (48 h) for carp 8.8 mg/l.