Ametryn 莠灭净

莠灭净

中文通用名称：莠灭净
化学名称：N-2-乙氨基-N-4-异丙氨基-6-甲硫基-1，3，5-三嗪
其它中文名称：阿灭净
CAS登记号：834-12-8
规格：97%原药，水份≤1%，盐份≤1%
应用：选择性除草剂，苗前苗后使用,防除香蕉、柑桔、咖啡、可可、玉米、油棕、凤梨、甘蔗、茶、马铃薯和非耕地中阔叶和禾本科杂草。

一、产品性能：
本品为一种三氮苯类选择性内吸传导型除草剂。无色结晶。在水中的溶解度为185mg/L（20℃）。可溶于有机溶剂。与强酸、强碱水解形成6-羟基体。对植物的光合作用有抑制作用，属选择性除草剂。杀草作用迅速，可被0-5厘米土壤吸附，形成药层，使杂草萌发出土时接触药剂。对刚萌发的杂草防效最好。用于防治玉米、甘蔗田的马唐、狗尾草等一年生杂草杂草田间杂草。

二、剂型：可湿性粉剂。

三、毒性：大鼠口服LD501405mg/kg。对鱼毒性强。日本农药注册保留标准规定果品为0.4mg/kg。

四、使用技术和使用方法：
作物 防治对象 制剂用药量 使用方法
玉米田 一年生杂草 1800-2700克/公顷 120-180克/亩 播后苗前
土壤喷雾
甘蔗田 一年生杂草 1800-2700克/公顷 120-180克/亩 种后苗前
土壤喷雾

五、注意事项：
1.本品用于苗前土壤喷雾处理，每季最多使用一次。
2.本品未经试验不可与其它农药混用。
3.施药时穿戴必要的防护用具，尽量避免皮肤与农药接触，顺风施药，避免逆风施药，施药后用肥皂洗净脸、手及裸露的皮肤和衣物，施药时不可吸烟或饮食。
4.用剩后药液应妥善处理，禁止倒入池塘，避免对水源和鱼的影响。
六、中毒急救：
施药时要戴面罩及手套。如药物溅到皮肤或衣物上，要用肥皂和清水冲洗；误服要立即送医院对症治疗

ametryn
Herbicide
HRAC C1 WSSA 5; 1,3,5-triazine

NOMENCLATURE
Common name ametryn (BSI (since 1984), E-ISO, ANSI, WSSA, JMAF); ametryne (BSI (before 1984), (f) F-ISO)
IUPAC name N2-ethyl-N4-isopropyl-6-methylthio-1,3,5-triazine-2,4-diamine
Chemical Abstracts name N-ethyl-N'-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine
CAS RN [834-12-8] EEC no. 212-634-7 Development codes G 34 162 (Geigy)

PHYSICAL CHEMISTRY
Composition 96% pure. Mol. wt. 227.3 M.f. C9H17N5S Form White powder. M.p. 86.3-87.0 ºC B.p. 337 °C/98.6 kPa V.p. 0.365 mPa (25 ºC) (OECD 104) KOW logP = 2.63 (25 ºC) Henry 4.1 ´ 10-4 Pa m3 mol-1 (calc.) S.g./density 1.18 (22 ºC) Solubility In water 200 mg/l (20 ºC). In acetone 610, methanol 510, toluene 470, n-octanol 220, hexane 12 (all in g/l, 25 ºC). Stability Stable in neutral, weakly acidic, and weakly alkaline media. Hydrolysed by strong acids (pH 1) and alkalis (pH 13) to the herbicidally-inactive 6-hydroxy derivative. Slowly decomposed by u.v. light. pKa 4.1, weak base

COMMERCIALISATION
History Herbicide reported by H. Gysin & E. Knüsli (Adv. Pest Control Res., 1960, 3, 289). Introduced by J. R. Geigy S.A. (now Syngenta AG). Patents GB 814948; CH 337019 Manufacturers Atanor; Crystal; Hegang Heyou; Hesenta; Makhteshim-Agan; Oxon; Sannong; Syngenta

APPLICATIONS
Biochemistry Photosynthetic electron transport inhibitor at the photosystem II receptor site. Mode of action Selective systemic herbicide, absorbed by the leaves and roots, with translocation acropetally in the xylem, and accumulation in the apical meristems. Uses Pre- and post-emergence control of most annual grasses and broad-leaved weeds in pineapples, sugar cane, bananas, citrus fruit, maize, cassava, coffee, tea, sisal, cocoa, oil palms, and on non-crop land. Application rates are in the range 2-4 kg/ha, except when used as a directed spray on maize. Also used as a potato haulm desiccant. Phytotoxicity Some sugar cane varieties show temporary chlorosis and scorching of lower leaves. Formulation types EC; FW; SC; WG; WP. Selected products: 'Evik' (USA) (Syngenta); 'Gesapax' (Syngenta); 'Ameflow' (Inquiport); 'Amesip' (Sipcam); 'Ametrex' (Makhteshim-Agan); mixtures: 'Krismat' (+ trifloxysulfuron-sodium) (Syngenta)

OTHER PRODUCTS
'Crisatrina' (Crystal); 'Mebatryne' (Bayer CropScience); 'Metrimex' (Sipcam) mixtures: 'Codal' (+ prometryn) (Syngenta); 'Ametrex Extra' (+ simazine) (Makhteshim-Agan); 'Ametron' (+ diuron) (Makhteshim-Agan); 'Amigan' (+ terbutryn) (Makhteshim-Agan); 'Atramet Combi' (+ atrazine) (Makhteshim-Agan)

ANALYSIS
Product analysis by glc with FID (CIPAC Handbook, 1998, H, 22; FAO Specification CP/61; AOAC Methods, 17th Ed., 971.08). Residues determined by glc (K. Ramsteiner et al., J. Assoc. Off. Anal. Chem., 1974, 57, 192; E. Knüsli, Anal. Methods Pestic. Plant Growth Regul. Food Addit., 1964, 4, 13; B. G. Tweedy & R. A. Kahrs, Anal. Methods Pestic. Plant Growth Regul., 1978, 10, 493). In drinking water, by glc with NPD; AOAC Methods, 17th Ed., 991.07.

MAMMALIAN TOXICOLOGY
Reviews J. Pest. Sci., 18(4), 1993 (in Japanese). Oral Acute oral LD50 for rats 1160 mg tech./kg. Skin and eye Acute percutaneous LD50 for rabbits >2020, rats >3100 mg/kg. Not a skin or eye irritant (rabbits). Not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for rats >5170 mg/m3 air. NOEL (2 y) for rats 50, for mice 10 ppm; (1 y) for dogs 200 ppm. ADI 0.015 mg/kg. Toxicity class WHO (a.i.) III; EPA (formulation) III EC classification Xn; R22| N; R50, R53

ECOTOXICOLOGY
Birds LC50 (5 d) for bobwhite quail and mallard ducks >5620 ppm. Fish LC50 (96 h) for rainbow trout 5, bluegill sunfish 19, channel catfish 25 mg/l. Daphnia LC50 (96 h) 28 mg/l. Algae EC50 (7 d) for Selenastrum capricornutum 0.0036 mg/l. Other aquatic spp. LC50 (96 h) for mysid shrimp (Mysidopsis bahia) 2.3 mg/l. Bees Low toxicity to bees; LD50 (oral) >100 mg/bee. Worms LC50 (14 d) for earthworms 166 mg/kg soil.

ENVIRONMENTAL FATE
Animals Irrespective of the dose or the dosing regime, most is excreted within 3 to 4 days. Conjugation with glutathione and dealkylation are the main metabolic pathways. Plants Metabolised by tolerant plants and, to a lesser extent, by sensitive plants, to non-toxic substances by replacement of the methylthio group by a hydroxy group, and by dealkylation of the amino groups. Soil/Environment Loss from soil is principally by microbial degradation (H. O. Esser et al., Herbicides: Chemistry, Degradation and Mode of Action, 1975, 1, 129). Median DT50 in soil 51 d (11-120 d). Koc 300; however column leaching studies indicate ametryn does not leach significantly. Degradation in aquatic systems is caused by microbial processes, with photolysis also contributing. Adsorption to the sediment is the most efficient mechanism of elimination of ametryn from water.